ageLOC Tru Face Peptide Retinol Refill

Supports smoother, younger, bouncier-looking skin.

Provides powerful results while being gentle enough for daily use.

Reduces pore appearance and helps visibly brighten skin and even skin tone.

Helps improve skin texture, reduce roughness, and deliver a smoother look and feel.

Reduces the appearance of fine lines and wrinkles.

2025 Allure Best of Beauty Award
- Formulated with a clinically tested anti-aging peptide that targets aging skin concerns.
- Features ageLOC technology to target the sources of aging.
- Individuals can be sensitive to any new skincare product, so always do a spot check and/or check with your dermatologist if you have sensitive skin.
- Formulated fragrance-free.
- Safety-dermatologist tested.
Always use sun protection during the day. Avoid contact with eyes, rinse if contact occurs.
How to switch refill bottle: Take off cap, unscrew pump from clear packaging, unscrew refill bottle from pump and screw on new refill bottle.
Apply to clean skin on face and neck each night. Follow with your favorite Nu Skin® moisturizer.
Water (Aqua), Glycereth-26, Dimethicone, Jojoba Esters, 1,2-Hexanediol, Coco-Caprylate/Caprate, C10-18 Triglycerides, Retinol, Hydroxypinacolone Retinoate, Oligopeptide-1, Oryza Sativa (Rice) Bran Extract, Narcissus Tazetta Bulb Extract, Oryza Sativa (Rice) Extract, Schizandra Chinensis Fruit Extract, Bisabolol, Rosmarinus Officinalis (Rosemary) Leaf Extract, Glycerin, 4-t-Butylcyclohexanol, Adenosine, Helianthus Annuus (Sunflower) Extract, Tocopherol, Glyceryl Stearate, Polysilicone-11, Allyl Methacrylates Crosspolymer, Butylene Glycol, Polysorbate 20, Ammonium Acryloyldimethyltaurate/VP Copolymer, PEG-40 Stearate, Polyisobutene, Cetearyl Alcohol, Dimethyl Isosorbide, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, PEG-7 Trimethylolpropane Coconut Ether, Dimethiconol, Decyl Glucoside, Pentylene Glycol, Ceteareth-20, Sorbitan Isostearate, Hydroxyacetophenone, Disodium EDTA, Sodium Hydroxide.

ageLOC Blend
An anti-aging complex that targets the sources of aging to preserve the look of youth.

Jojoba + 4TB Blend
A gentle blend that helps soothe and hydrate for calming skin relief.

Advanced Peptide Technology
First clinically tested, nature-identical anti-aging peptide discovered by AI that targets key signs of aging while boosting retinol benefits.

Potent Retinol Complex
Blend of stabilized pure retinol and retinoic acid ester (HPR) helps promote cell turnover to improve the appearance of lines and wrinkles, skin tone, texture, and elasticity—without the harsh side effects

Nu Skin conducted an 8-week in-house study where 31 male and female participants, ages 35–70, used ageLOC Tru Face Peptide Retinol Complex once nightly.
After just 1 week:
87% of participants agreed their skin looks/feels more energized and healthier,
83% of participants agreed their skin looks and feels rejuvenated,
80% of participants agreed their complexion looks brighter,
80% of participants agreed their pores look tighter, and 80% of participants agreed their skin feels comfortable and balanced. Plus, results improved over time.
After 8 weeks:
100% of participants agreed their wrinkles look filled in/less visible,
100% of participants agreed their skin has more youthful bounce and plumpness.
100% of participants agreed their blemishes are less visible,
97% of participants agreed pores look tighter,
97% of participants agreed the product is youth-promoting,
97% of participants agreed their skin looks luminous and clear, and 93% of participants agreed their complexion is brighter.
In addition, participants experienced measurable improvements* in the following traits:
64% improvement in elasticity,
38% improvement in skin barrier, and 20% improvement in firmness after just one use.
Nu Skin also commissioned a clinical study where 10 male and female subjects between the ages of 30 and 60 were recruited. Participants used ageLOC Tru Face Peptide Retinol Complex nightly on clean facial skin. ageLOC Tru Face Essence Ultra was used twice daily and applied after Peptide Retinol Complex at night. Expert grading was conducted, and images were taken.
After only 2 weeks, the expert grader noted the following:
70% of subjects showed reduction in fine lines/wrinkles.
60% of subjects showed reduction in appearance of pores.
60% of subjects showed reduction in undereye puffiness.
60% of subjects showed improvement in radiance/luminosity.
After 12 weeks, the expert grader noted the following:
100% of subjects showed improvement in skin texture.
90% of subjects showed reduction in fine lines/wrinkles.
90% of subjects showed reduction in appearance of pores.
90% of subjects showed improvement in skin contour/firmness/lifted appearance.
70% of subjects showed reduction in crow’s feet.
*Bioinstrumentation measurement data
Unlike many other retinol products on the market, our anti-aging facial serum is gentle—and can even be suitable for those with sensitive skin. It provides all the benefits that you’d want from a retinol product—and more—without the harsh side effects, like dryness, redness, flakiness, and skin irritation. It is also formulated with the first AI-discovered, nature-identical peptide that’s clinically proven to target aging skin concerns, which helps boost the effects of retinol. And finally, ageLOC Tru Face Peptide Retinol Complex contains two types of retinoids—stabilized pure retinol and retinoic acid ester—to help deliver maximum benefits. It also contains our proprietary ageLOC Blend, which targets the sources of aging to help maintain a youthful, vibrant appearance.
What is the Advanced Peptide Technology in ageLOC Tru Face Peptide Retinol Complex?
As humans, we are inherently limited in the amount of time we can spend researching ingredients. But using AI, we can identify the ideal ingredients to help maximize the benefits of our products quickly—and more effectively. Our Advanced Peptide Technology was the first clinically tested, nature-identical anti-aging peptide to be discovered using AI. This peptide works synergistically with retinol to boost its effectiveness. It’s also fast-acting and targets the key signs of aging, including visibly reducing pores and hyperpigmentation, as well as improving skin tone and texture and reducing the appearance of fine lines and wrinkles.
What does the Jojoba + 4 TB Blend do for my skin?
The Jojoba Esters and 4TB (a soothing molecule) in this facial serum help to soothe and hydrate skin so that you can enjoy great retinol benefits without the aggressive side effects.
What’s important about the types of Retinols used in ageLOC Tru Face Peptide Retinol Complex?
There are four main types of retinoids: retinoic acid, retinaldehyde (sometimes referred to as retinal), retinol, and retinyl esters. They vary in potency and strength, with retinoic acid being the most potent and retinyl esters being the least. Retinoic Acid is the most potent because it is the most active form of vitamin A, but it is irritating for most skin types and is not available for use in many markets. Our retinol serum is formulated with retinoic acid ester, a next-gen version of retinoic acid that doesn’t irritate the skin. ageLOC Tru Face Peptide Retinol Complex also contains stabilized pure retinol for maximum benefits with the least amount of irritation.
When should I use ageLOC Tru Face Peptide Retinol Complex?
You should use ageLOC Tru Face Peptide Retinol Complex once per day, in your night skincare routine. Because you may experience increased sun sensitivity—especially during the first few weeks of use—we recommend limiting your sun exposure. Also, make sure to wear sunscreen daily, especially when using any retinol product.
Can people with sensitive skin use ageLOC Tru Face Peptide Retinol Complex?
Our facial serum was specially formulated to be gentle and soothing to skin, so even people with sensitive skin can experience the benefits. However, individuals can be sensitive to any new skincare product, so do a spot check and/or check with your dermatologist if you have sensitive skin.

We want you to be confident about the ingredients in your products. Visit our ingredient dictionary to learn more about what makes Nu Skin products amazing.

Refill system designed to reduce carbon footprint and packaging waste.
72% reduction of packaging per refill in comparison to typical single-use glass packaging.
53% reduction in annual packaging waste in comparison to typical single-use glass packaging.
Refill cartridge made with 100% recycled material.
Refill system avoids 572 tons of carbon emissions compared to typical single-use glass packaging, based on projected annual global sales.
As part of our efforts to be a Force for Good in the world, Nu Skin is working to improve the environmental and social impact of our products—both inside and out!

At Nu Skin, we’re commiteted to keeping our global communities clean, safe, and protected for the future. We’re proud to embrace sustainable practices today for a resource-rich tomorrow.

RESOURCE EFFICIENCY
Nu Skin is committed to embracing sustainable practices today to enhance a resource rich tomorrow by being resource efficient. We’re working to improve our waste diversion at corporate headquarters through proper waste management and recycling.
NU SKIN SUSTAINABLE PRODUCTS CAMPAIGN

Recycle Right
Nu Skin designed the Recycle Right resources to help you improve your impact by responsibly disposing of Nu Skin products.

Sustainable Products
Nu Skin is committed to creating recycled, recyclable, reusable, reduced, or renewable packaging, and with your help, we can keep our planet healthy.

Ingredients Philosophy
Nu Skin formulate every product in the Nu Skin portfolio to 6S Quality Standards, which includes the safety and transparency of all ingredients.



NU SKIN AT A GLANCE
Nu Skin Enterprises, Inc. (NYSE: NUS) is a global integrated beauty and wellness company, powered by a dynamic affiliate opportunity platform. The company helps people look, feel and live their best with products that combine the latest insights of science, technology and nature. Backed by nearly 40 years of scientific research, Nu Skin develops innovative products for personal care, nutrition and anti-aging.
INNOVATION
At Nu Skin, we embrace constant evolution, recognizing the ever-changing needs of our customers, and adapting our skincare and wellness offerings accordingly. Our commitment to innovation is exemplified by the groundbreaking ageLOC science, a revolutionary anti-aging research and technology that has not only given rise to some of our most cherished products and devices but has also reshaped the industry.


RESEARCH CENTRES AND LABORATORIES
Nu Skin aims to make history with two cutting-edge facilities— the 2044 m2 Centre for Anti-Ageing Research in Provo, housing five state-of-the-art labs, and the 1900 m2 Greater China Innovation Park in Fengxian, China, featuring six labs and over 20 research scientists. These facilities drive ongoing innovation and development, crucial for providing advanced well-being and skincare solutions.
CLINICAL TRIALS
While we have utmost confidence in the quality of our products at Nu Skin, we understand the importance of substantiating our claims. That’s why we consistently commission professional third-party clinical studies to validate the efficacy of our skincare lines, and you can find the transparent results showcased on our individual webshop pages.
SCIENTIFIC ADVISORY BOARD AND IN-HOUSE SCIENTISTS
At Nu Skin, we actively seek collaboration with the brightest scientific minds. Our products undergo thorough research, testing, and development by a global team of over 75 in-house scientists, guided by our esteemed Scientific Advisory Board. Comprising experts from diverse fields, this collective think tank offers unique insights that drive our ongoing innovation, ensuring the delivery of novel and compelling products well into the future.
FORCE FOR GOOD
A fundamental aspect of Nu Skin’s mission is to be a force for good throughout the world.

One-Time order (Standard Shipping) – US$5.99
Subscription order (Standard Shipping) – US$2.99
DELIVERY TIMES:
Standard Shipping is 2-6 Days
Delivery time may vary depending on location and can take up to 10 days.
Complete your order by 2:00pm (MT) to ship same business day
Orders placed after 2:00pm (MT) will ship the following business day
Orders placed on the weekend are shipped the following business day

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